Vandazole is a brand of prescription metronidazole vaginal gel 0.75% FDA-labeled for bacterial vaginosis (BV) in post-menarchal females. Its defining features are the vaginal route, 0.75% concentration and applicator-based administration—not the familiar metronidazole ingredient alone. A tube of topical MetroGel used for rosacea or a box of oral tablets is a different medicine for dispensing purposes, even when the same active ingredient appears on the packaging. See the vaginal metronidazole product hub for the broader family.
The U.S. Vandazole label specifies a 70 g tube with five vaginal applicators; each full applicator delivers about 5 g of gel (37.5 mg metronidazole). The label describes once-daily intravaginal administration for five days. These facts identify the packaged product and are not individualized prescribing instructions. The CDC includes a 0.75% metronidazole vaginal-gel regimen among recommended BV treatments, but the prescription and the product-specific label should control an individual patient's use. A pharmacy search showing Vandazole alongside generic vaginal gels and Nuvessa 1.3% does not mean all three represent the same concentration, package or administration schedule.
This Vandazole page focuses on the branded 0.75% product, the relationship to approved generic 0.75% vaginal gels, package verification and prescription access. Readers already comparing several vaginal products should use Nuvessa versus Vandazole; readers checking a specific prescription can use the vaginal-gel pharmacy guide. This page is not a source of live retailer inventory.
Vandazole is metronidazole formulated for intravaginal administration at a concentration of 0.75%. Concentration must be read together with the route and product label. The gel is designed for local vaginal use, not for oral ingestion or application to facial rosacea lesions. The prescription, label and pharmacist should agree on the medicine being dispensed, including its route and applicator instructions.
A search result that says 'metronidazole gel 0.75%' can refer to a vaginal product or a dermatologic product. This ambiguity is particularly important when buying through catalog-style pharmacy interfaces. Request an explicit vaginal-route descriptor; do not try to determine route solely from percentage strength.
| Name or product type | Labeled route or form | Key distinction |
|---|---|---|
| Vandazole 0.75% | Prescription vaginal gel | Branded 0.75% vaginal formulation with applicator instructions |
| Generic metronidazole vaginal gel 0.75% | Prescription vaginal gel | Potential approved generic products; verify exact package |
| Nuvessa 1.3% | Prescription vaginal gel | Different concentration and single-dose presentation |
| MetroGel 1% | Prescription topical skin gel | Rosacea product; not a vaginal replacement |
Vandazole is a branded product entity, while generic 0.75% metronidazole vaginal gel products may be marketed under different labelers and identifiers. FDA approval and therapeutic-equivalence assessments apply to particular products, not to a category name in a shopping filter. A pharmacy may offer a generic where legally appropriate, but the exact order and state substitution rules still matter.
When discussing a brand-to-generic change, compare route, active ingredient, concentration, supplied applicators and labeled product identity. Generic 0.75% gel is not a universal substitute for 1.3% Nuvessa simply because both contain metronidazole. For the generic-specific context rather than a brand history, see generic vaginal metronidazole gel.
Vandazole's clinical context is bacterial vaginosis, a condition that requires appropriate assessment. Vaginal discharge or odor can have causes other than BV, and some conditions require entirely different testing and therapy. The fact that metronidazole is used for several infections by other routes does not mean this vaginal gel is appropriate for those infections.
CDC guidance identifies vaginal metronidazole 0.75% as an option for symptomatic BV; it separately describes treatment for trichomoniasis, where relying on vaginal metronidazole gel is not appropriate. Readers should use the BV treatment context for clinical decision frameworks, not treat a brand label as permission to self-diagnose.
Nuvessa contains metronidazole in a 1.3% vaginal gel designed for a single-dose, prefilled applicator. Vandazole is a 0.75% product with a different labeled administration framework. Product concentration and regimen are both important; changing one without the other is not a routine substitution. Follow the actual clinician-directed prescription, not a comparison of percentages alone.
An FDA-approved 1.3% generic exists, but that regulatory fact does not turn it into a generic of Vandazole 0.75%. The relevant reference products and formulations differ. Pharmacy selection should therefore begin with the route, concentration, brand or generic permission, package and directions, rather than the single search word 'metronidazole.'
Vandazole specifically comes as a 70 g gel tube with five vaginal applicators in the cited U.S. label. This should be checked against any pharmacy listing; other vaginal metronidazole brands or generic labels may describe different packages. A pharmacy order should identify not just the drug and strength but also the quantity and supplied applicators or delivery system. If a seller lists a tube without clear information about vaginal use or the applicator, that is a reason to ask for the exact product description rather than assuming the package will be suitable.
For a prescription already issued, ask the pharmacist to confirm the product identifier, concentration, package size and complete components before payment or delivery. A brand photograph can show a historical carton, and an approved package's marketing information does not prove that a particular branch currently stocks it.
A clinician should assess symptoms, medical history and any need for examination or testing before prescribing vaginal therapy. Once a valid order identifies Vandazole or a suitable 0.75% vaginal gel, the dispensing pharmacy verifies that it can supply the correct medicine. A pharmacy is not a substitute for the clinical step, and an online consultation does not guarantee a gel prescription.
For a narrower explanation of obtaining the prescription, use vaginal metronidazole prescription requirements. If the product cannot be filled, the pharmacist may contact the clinician to clarify an approved generic or other clinically appropriate plan; patients should not swap products by themselves.
Read Vandazole's full prescribing information for contraindications and precautions. Local irritation or other adverse effects may occur, and patient-specific factors such as pregnancy, concomitant medicines or recurring symptoms can change the clinician's assessment. Instructions for a vaginal product should not be inferred from oral Flagyl or a rosacea gel insert even though all contain metronidazole.
If symptoms persist, return or change, speak with a healthcare professional. Reusing a previously dispensed applicator or starting another course without assessment may obscure a different diagnosis. Product information is educational and cannot replace the care required for a specific patient.
DailyMed can identify Vandazole's labeled active ingredient, route and product presentation. The FDA Orange Book can help with specific approval and generic questions. Neither database reports what is on a local pharmacy shelf today. Distributors, pharmacy networks and insurance requirements may affect fulfillment independently of what a public label displays.
The vaginal gel availability guide addresses how to verify a precise listing. Ask for the exact brand or approved generic and its concentration. Do not treat a promotional 'available now' banner as sufficient verification of licensure, valid prescription requirements or actual supply.
Patient cost may vary with branded versus generic dispensing, quantity, insurance network, plan restrictions and pharmacy fees. A cash-price search that combines different strengths or vaginal and skin gels is not reliable. Checking the right medicine comes before comparing prices, particularly where an alternative could require a new prescription.
For a long-lived cost framework, see Vandazole pricing factors. No price shown here should be interpreted as a live quote or confirmation of an offer. Ask an eligible pharmacy for the actual price tied to the precise product and prescription.
Before accepting a product, verify the valid prescription, 'vaginal' route, 0.75% concentration, brand or approved generic decision, quantity and applicator details. Ask the pharmacist how the package instructions correspond to the clinician's order. If a label says dermal, rosacea, 1%, or 1.3%, pause and clarify rather than assuming a harmless difference.
The purpose of these checks is product accuracy. They do not authorize self-prescribing, determine which BV treatment to use or guarantee that a branded package is available. When an important identifier is missing, obtain professional clarification before use.
Vandazole is a branded prescription metronidazole vaginal gel 0.75% used in bacterial vaginosis care.
No. Vandazole is formulated for vaginal use; topical MetroGel is applied to skin for rosacea and is not an intravaginal substitute.
No. Nuvessa is a 1.3% single-dose vaginal gel, while Vandazole is a 0.75% vaginal product with different labeling and instructions.
FDA-approved generic 0.75% vaginal gels exist. A pharmacist must check the exact product and permitted substitution under the prescription.
Vandazole is a vaginal gel associated with BV care. Trichomoniasis requires its own diagnosis and appropriate therapy; do not use this gel as a substitute for a systemic prescribed regimen.
No. Vaginal metronidazole products are prescription medicines in the United States.
No. Published labeling describes a product but does not show a pharmacy’s real-time supply.
The dispensed product should match the formulation, package components and instructions specified for the prescription. Confirm any unclear applicator details with the pharmacist.
Do not switch formulations or brands without pharmacy review and any required clinician authorization.
Brand versus generic status, actual package, insurance rules and eligible pharmacy can change the amount paid. Verify a quote for the specific prescription.